Synthesis of several 2-(5-chloro-3-methyl-1-(pyridin-2-yl) pyrazolidin-4-yl)-3- substituted phenylthiazolidin-4-ones as prospective antimicrobial agents
Ranjana Dubey, Nidhi Chaudhary, Hament Panwar
Corresponding Author : Hament Panwar,
Department of Chemistry, S.R.M. University, U.P., India.
Email ID : firstname.lastname@example.org
Received : 2013-12-26 Accepted : 2013-12-28 Published : 2014-01-02
Abstract : Several 2-(5- chloro-3- methyl-1- (pyridin-2-yl) pyrazolidin-4-yl)-3- substitutedphenylthiazolidin -4-one (4a-f) have been synthesized by conventional synthesis methodology. The synthesized derivatives were characterized by IR, 1H-NMR, Mass and elemental analysis (C, H, N) . Furthermore the synthesized 2-(5-chloro-3-methyl-1-(pyridin-2-yl) pyrazolidin-4-yl)-3- substitutedphenylthiazolidin-4-one (4a-f) were tested for antimicrobial activities. The compound 4c displayed significant biological activities among the all tested derivatives.
Keywords : Antibacterial, antifungal, thiazolidin-4-one, acute toxicity.
Citation : Hament Panwar(2013). Synthesis of several 2-(5-chloro-3-methyl-1-(pyridin-2-yl) pyrazolidin-4-yl)-3- substitutedphenylthiazolidin-4-ones as prospective antimicrobial agents. J. of Modern Drug Discovery And Drug Delivery Research. V1I1. DOI : 10.5281/zenodo.913109
Copyright : © 2013 Hament Panwar, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
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