Synthesis of several 2-(5-chloro-3-methyl-1-(pyridin-2-yl) pyrazolidin-4-yl)-3- substituted phenylthiazolidin-4-ones as prospective antimicrobial agents
Ranjana Dubey, Nidhi Chaudhary, Hament Panwar
Corresponding Author : Hament Panwar,
Department of Chemistry, S.R.M. University, U.P., India.
Email ID : firstname.lastname@example.org
Received : 2013-12-26 Accepted : 2013-12-28 Published : 2013-12-28
Abstract : Several 2-(5- chloro-3- methyl-1- (pyridin-2-yl) pyrazolidin-4-yl)-3- substitutedphenylthiazolidin -4-one (4a-f) have been synthesized by conventional synthesis methodology. The synthesized derivatives were characterized by IR, 1H-NMR, Mass and elemental analysis (C, H, N) . Furthermore the synthesized 2-(5-chloro-3-methyl-1-(pyridin-2-yl) pyrazolidin-4-yl)-3- substitutedphenylthiazolidin-4-one (4a-f) were tested for antimicrobial activities. The compound 4c displayed significant biological activities among the all tested derivatives.
Keywords : Antibacterial, antifungal, thiazolidin-4-one, acute toxicity.
Citation : Hament Panwar (2013). Synthesis of several 2-(5-chloro-3-methyl-1-(pyridin-2-yl) pyrazolidin-4-yl)-3- substitutedphenylthiazolidin-4-ones as prospective antimicrobial agents. J. of Modern Drug Discovery And Drug Delivery Research. V1:I1.05 DOI : 10.5281/zenodo.913109
Copyright : © 2013 Hament Panwar, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Journal of Modern Drug Discovery and Drug Delivery Research
ISSN : 2348-3776
Volume 1 / Issue 1
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