Synthesis and SAR Study of 2-(4-cyano-2-methylphenoxy)acetohydrazide

Research Article

Synthesis and SAR Study of 2-(4-cyano-2-methylphenoxy)acetohydrazide

Bapu R Thorat

Corresponding Author : Bapu R Thorat

Department of Chemistry, Government of Maharashtra’s Ismail Yusuf College of Arts, Science and Commerce, Mumbai – 60, India.

Email ID : iycbrthorat78@gmail.com

Received : 2018-04-15 Accepted : 2018-06-29 Published : 2018-06-29

Abstract : In drug development process, if physical sample is limited then computer models constitutes valid alternative to experiment. Here, we used different web tools such as ChemDraw, Spartan, Cresset, Avogadro, MarvinSketch 18.10, Forge, SwissADME, SwissTargetPrediction, Swiss Similarity, and Molinspiration, etc. to predict drugllikeness character of the hydrazide. The 2-(4-cyano-2-methylphenoxy)acetohydrazide was synthesized from 4-cyano-2-methylphenol and study their antimicrobial activity.

Keywords : Avogadro, Statron, Forge, SwissADME, Antimicrobial, Hydrazine

Citation : Bapu R Thorat (2018). Synthesis and SAR Study of 2-(4-cyano-2-methylphenoxy)acetohydrazide. j. of Physical and Chemical Sciences.V6I3-03. DOI : 10.5281/zenodo.1303032

Copyright : © 2018 Bapu R Thorat . This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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