Synthesis and Antimicrobial Activity Analysis of Substituted Thiadiazepines

Research Article

Synthesis and Antimicrobial Activity Analysis of Substituted Thiadiazepines

Ravindra Kumar, Tlak Ram, Hament Panwar

Corresponding Author : Hament Panwar,

Department of Chemistry, Sri Venkateshwara University, Amroha-244236, U.P., India.

Email ID : dr_h.panwar@rediffmail.com

Received : 2014-08-02 Accepted : 2014-09-03 Published : 2014-09-04

Abstract : Several 7-methyl-3-substitutedphenyl-9- (pyridin-2-yl)-7, 8, 9, 9a-tetrahydro-6aH-pyrazolo (4,3-f) (1,2,4) triazolo (3,4-b) (1,3,4)- thiadiazepines 4 (a-f) have been synthesised by using conventional methodology. The synthesized derivatives were characterized by IR, 1H-NMR, Mass and elemental analysis (C, H, N). Furthermore the synthesized substituted thiadiazepines 4(a-f) were biologically evaluated for antimicrobial activities.

Keywords : Antibacterial, antifungal, thiazolidin-4-one, acute toxicity

Citation : Hament Panwar, et al (2014), Synthesis and Antimicrobial Activity Analysis of Substituted Thiadiazepines. J. of Modern Drug Discovery and Drug Delivery Research. V2I1 DOI : 10.5281/zenodo.1000034

Copyright : © 2014 Hament Panwar. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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