Pyrazolone Thiosemicarbazone Based Metal Complexes: Physico-Chemical Study, Synthesis and Biological Activity

Research Article

Pyrazolone Thiosemicarbazone Based Metal Complexes: Physico-Chemical Study, Synthesis and Biological Activity

Rashmi B. Patel, Dhanji P. Rajani, Smita D. Rajani, Hitesh D. Patel

Corresponding Author : Hitesh D. Patel,

Department of Chemistry, School of Science, Gujarat University, Ahmedabad-380009, Gujarat, India

Email ID : drhiteshpatel@gmail.com

Received : 2015-06-01 Accepted : 2015-07-09 Published : 2015-07-09

Abstract : In this article we have reported physico-chemical study of 2-((3-methyl -5- oxo -1- phenyl -4,5-dihydro-1H-pyrazol-4-yl)(phenyl)methylene)hydrazinecarbothioamide with various metal ions such as Cu(II), Cr(II), Mn(II), Pd(II), Co(II), Ni(II), Pb(II) and Hg(II) by two methods spectrophotometry and conductometry. The study said that metal:ligand ratio is 1:1 and the further conformation is done by spectral analysis. We have also screened our compounds for antibacterial, antifungal and antimalarial activity.

Keywords : pyrazolone-thioemicarbazone, metal complexes, physico-chemical study, antibacterial, antifungal, antimalarial activity.

Citation : Hitesh D. Patel et al.. (2015) Pyrazolone Thiosemicarbazone Based Metal Complexes: Physico-Chemical Study, Synthesis and Biological Activity j. of Physical and Chemical Sciences.V3I2.01. DOI : 10.5281/zenodo.999911

Copyright : © 2015 Hitesh D. Patel. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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