Pentadiplandra brazzeana Baill. (Pentadiplandraceae): Chemical screening assessment and a mini-review on its Bioactivity and Phytochemistry

Research Article

Pentadiplandra brazzeana Baill. (Pentadiplandraceae): Chemical screening assessment and a mini-review on its Bioactivity and Phytochemistry

Koto-te-Nyiwa Ngbolua Nathanael N. Kongobi, Charles T. Nzewe, Colette Masengo Ashande, Clément L. Inkoto, Georges L. Lufulwabo, Gédéon N. Bongo, Désiré W. Konga

Corresponding Author : Koto-te-Nyiwa Ngbolua,

Faculté des Sciences, Université de Kinshasa, BP 190 Kinshasa XI, République Démocratique du Congo.

Email ID : jpngbolua@unikin.ac.cd

Received : 2018-04-02 Accepted : 2018-05-15 Published : 2018-05-15

Abstract : In Africa, about 80% of population relies on traditional medicine for their health care purpose. The aim of the present study was to evaluate the chemical composition of the plant species Pentadiplandra brazzeana Baill. used as dietary and medicinal plant by indigenous people in the Province of Nord-Ubangi and to provide update knowledge on phytochemistry and bioactivity of this plant species. A literature search was conducted to obtain information about the phytochemistry and pharmacognosy of Pentadiplandra brazzeana from various electronic databases (PubMed, PubMed Central, Science Direct and Google scholar). The scientific name of this plant species was used as a keyword for the search, along with the terms phytochemistry and pharmacognosy. The chemical structures of the P. brazzeana naturally occurring compounds were obtained from PCIDB (PhytoChemical Interactions DB) or drawn using ChemBioDraw Ultra 12.0 software package. Phytochemical screening revealed the presence of alkaloids, linked quinones, saponins, tannins and triterpenoids in both the leaves and roots. While anthocyanis, flavonoids and leuco-anthocyanins are present in the leaves but absent in the roots. Findings revealed that this plant is traditionally used in African folk medicine to treat various ailments including intestinal parasitic diseases and against Chlamydiae. The roots are used for food flour preservation. These roots smelling a raifort pungent odor are edible because of their sweet taste. The ethnopharmacological relevance of this plant species is due to the presence of sulfur-containing phytochemicals. The present study can, therefore, help inform future scientific research towards the development of novel drugs of relevance from P. brazzeana for the improvement of human health and wellbeing.

Keywords : Ethno-medicine, medicinal plants, Pentadiplandra brazzeana, sulfur-containing phytochemicals, Democratic Republic of the Congo.

Citation : Koto-te-Nyiwa Ngbolua et al. (2018). Pentadiplandra brazzeana Baill. (Pentadiplandraceae): Chemical screening assessment and a mini-review on its Bioactivity and Phytochemistry, DR Congo. J. of Advancement in Medical and Life Sciences. V6I4.01. DOI : 10.5281/zenodo.1250435

Copyright : © 2018 Koto-te-Nyiwa Ngbolua. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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