Microwave Assisted Organic Synthesis (MWAOS) of a series of Dihydroquinazolinones and Dihydrocinnolinols.

Research Article

Microwave Assisted Organic Synthesis (MWAOS) of a series of Dihydroquinazolinones and Dihydrocinnolinols.

Abhilash Mullasseril

Corresponding Author : Abhilash Mullasseril

Veliyanad Post, Ernakulam Dist, Kerala-682313, India.

Email ID : mabhilash@hotmail.com

Received : 2014-01-15 Accepted : 2014-01-28 Published : 2014-01-28

Abstract : The present study concentrates on the synthesis of a series of dihydroquinazolinones and dihydrocinnolinols by applying the green concept Microwave Assisted Organic Synthesis (MWAOS) with high atom economy and the effect of substituents on deciding the product. A series of phenyl substituted 2-(phenylmethylidene) amino phenols are coupled with isatoic anhydride using a Microwave oven. A systematic computational study was conducted in designing and modelling the products and the reaction conditions. The practical application of artificial intelligence in designing the reactions was successfully tested and implemented.

Keywords : Solvent free synthesis; Microwave Assisted Organic Synthesis (MWAOS); isatoic anhydride;

Citation : Abhilash Mullasseril(2014) Microwave Assisted Organic Synthesis (MWAOS) of a series of Dihydroquinazolinones and Dihydrocinnolinols. J. of Bioprocessing and Chemical Engineering. V1I1. DOI : 10.5281/zenodo.1009593

Copyright : © 2014 Abhilash Mullasseril. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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