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%20%20%20%20In%20vitro%20Antioxidant%20Activity%20of%20Essential%20Oil%20and%20Polar%20and%20Non-Polar%20Extracts%20of%20Ocimum%20%20canum%20from%20Mbuji-Mayi%20DR%20Congo
Research article
  

In vitro Antioxidant Activity of Essential Oil and Polar and Non-Polar Extracts of Ocimum canum from Mbuji-Mayi DR Congo


D. D. Tshilanda, D.V. Onyamboko, D.S.T. Tshibangu, K.N. Ngbolua, P. V. Tsalu, P.T. Mpiana

1Department of Chemistry, Faculty of Science, University of Kinshasa, P.O. Box 190 Kinshasa XI, Democratic Republic of the Congo
2Department of Biology, Faculty of Science, University of Kinshasa, P.O. Box 190 Kinshasa XI, Democratic Republic of the Congo.


Corresponding author :

Mpiana P.T,
Phone: +243818116019,
Email:

Received: July 25, 2015,   Accepted: September 17, 2015,   Published: September 17, 2015.


Abstract:

DPPH radical scavenging activity of essential oil from fresh leaves of Ocimum canum Sims as well as methanolic, ethyl acetate, dichloromethane and n-hexane crude extracts, from dried leaves were analysed. The methanolic extract has the low IC50 so the strongest radical scavenging activity among extracts of Ocimum canum with IC50 values of 0.0234 mg.mL-1. Ethyl acetate , Dichloromethane and essential oil showed respectively IC50 values of 0.0767, 0.1938 and 1.4217 mg.mL-1. So, polar extracts exhibited stronger antioxidant activity than none-polar ones. None-polar solvents have provided fewer extraction yields than polar. The GC-MS analysis of the essential oil of Ocimum canum has been done and led to the identification of 1,8-Cineole as major compound


Keywords: antioxidant activity, Ocimum canum, essential oil, polar and non-polar extracts


Citation:

Mpiana P.T et al. (2015). In vitro Antioxidant Activity of Essential Oil and Polar and Non-Polar Extracts of Ocimum canum from Mbuji-Mayi DR Congo . J. of Advancement in Medical and Life Sciences. V3I3 DOI: 10.15297/JALS.V3I3.04


Copyright:

© 2015 Mpiana P.T. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.


      
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      Journal of Advancement in Medical and Life Sciences