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%20%20%20%20Protein%20Biomarkers:%20In%20Life%20and%20After%20Life
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Protein Biomarkers: In Life and After Life


Archana Moon, Neha Bhale, G.B. Shinde, Pallavi Sahare, Komal Talreja

1, 3, 4, 5 University Department of Biochemistry, RTM Nagpur University, Nagpur- 440033, India.
2, ACA, Regional Forensic Science Laboratory, State of Maharashtra, Nagpur, India.


Corresponding author :

Archana Moon,
Associate Professor,
University Department of Biochemistry,
RTM Nagpur University, Nagpur- 440033, India.
Contact no: +91-7798744244
Email:

Received: April 21, 2014,   Accepted: May 10, 2014,   Published:


Abstract:

Living humans, elicit certain specific biochemical parameters characteristic of their physiological state. Similarly, various changes in the chemical composition occur in the body after death. Some of these biochemical parameters can be used as biomarkers both for disease diagnosis as well as for gaining a deep understanding of the changes during post-mortem. Biomarkers thus help in understanding the physiological state of an individual, the progression of disease, the effectiveness of various treatments that are targeted to cure the disease, the prognosis of such diseases as osteoarthritis, post-polio syndrome, ovarian cancer, osteosarcoma, alzheimer’s disease etc. Post-mortem degradation products such as amino acids, hypoxanthine, volatile organic compounds and various proteins are some biomarkers that are used to understand the phenomenon of post-mortem.


Keywords: Biomarkers; Proteins; Disease; Postmortem; Decomposition.


Citation:

Archana Moon , et al (2014). Protein Biomarkers: In Life and After Life. J. of Advancement in Medical and Life Sciences. DOI: 10.15297/JALS.V1I3.01


Copyright:

© 2014 Archana Moon. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.


      
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      Journal of Advancement in Medical and Life Sciences