Antimicrobial study of polymeric ligands derived from 2, 4-dihydroxy acetophenone and their lanthanide (III) polychelates

Research Article

Antimicrobial study of polymeric ligands derived from 2, 4-dihydroxy acetophenone and their lanthanide (III) polychelates

Vijay R. Patel, Vijay D. Chavada, Jayantilal D, Joshi, Vasant M. Patel, Pranav S. Shrivastav.

Corresponding Author : Pranav S. Shrivastav,

Department of Chemistry, School of Sciences, Gujarat University.

Email ID : pranav_shrivastav@yahoo.com

Received : 2014-01-07 Accepted : 2014-01-18 Published : 2014-01-19

Abstract : In the present work, antimicrobial activities of five polymeric ligands derived from 2,4-dihydroxy acetophenone (DHAP-ED, DHAP-1,2 PD, DHAP-1,3 PD, DHAP-1,3 BD and DHAP-1,4 BD) and its polychelates with La3+, Pr3+, Nd3+, Sm3+, Gd3+, Tb3+ and Dy3+ have been studied. Agar diffusion method has been used to determine antimicrobial activity, and the organisms used were Escherichia coli, Bacillus substilis, Staphylococcus aureus (bacteria) and Sanccharomyces cerevisiae (yeast). Some important aspects viz. effect of pH, size of inoculums, and choice and ingredient of culture media were also taken into consideration while assessing the antimicrobial activities. From the results it was indicated that the polychelates possess higher antimicrobial activity compared to polymeric ligands primarily due to sharing of electron and increased lipophilicity of the polychelates.

Keywords : Phenolic ligands; 2,4-dihydroxyacetophenone; Antimicrobial study; Polychelates; Lanthanides.

Citation : Pranav S. Shrivastav(2014) Antimicrobial study of polymeric ligands derived from 2, 4-dihydroxy acetophenone and their lanthanide (III) polychelates. j. of Physical and Chemical Sciences.V1I1.05. DOI : 10.5281/zenodo.1000091

Copyright : © 2014 Pranav S. Shrivastav, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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