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Synthesis and Antimicrobial Activity Analysis of Substituted Thiadiazepines
Research article
  

Synthesis and Antimicrobial Activity Analysis of Substituted Thiadiazepines


Ravindra Kumar, Tlak Ram, Hament Panwar

1 Department of Chemistry, Sri Venkateshwara University, Amroha-244236, U.P., India
2Department of Chemistry, Govt. P.G. College, Uttarkashi-249193, U.K., India.
3Department of Chemistry, Neelkanth Institute of Technology, Modipuram-250110, Meerut, U.P., India


Corresponding author :

Hament Panwar,
Email:

Received: August 2, 2014,   Accepted: September 3, 2014,   Published:


Abstract:

Several 7-methyl-3-substitutedphenyl-9- (pyridin-2-yl)-7, 8, 9, 9a-tetrahydro-6aH-pyrazolo (4,3-f) (1,2,4) triazolo (3,4-b) (1,3,4)- thiadiazepines 4 (a-f) have been synthesised by using conventional methodology. The synthesized derivatives were characterized by IR, 1H-NMR, Mass and elemental analysis (C, H, N). Furthermore the synthesized substituted thiadiazepines 4(a-f) were biologically evaluated for antimicrobial activities


Keywords: Antibacterial, antifungal, thiazolidin-4-one, acute toxicity.


Citation:

Hament Panwar, et al (2014), Synthesis and Antimicrobial Activity Analysis of Substituted Thiadiazepines. J. of Modern Drug Discovery and Drug Delivery Research. V2I1. DOI: 10.15297/JMDDR.V2I1.01


Copyright:

© 2014 Hament Panwar. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.


      
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      Journal of Modern Drug Discovery and Drug Delivery Research