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Microwave Assisted Alternate Synthesis of a Series of Azomethine Derivatives of a Presently Prescribing Semisynthetic Aminopenicillin (Amoxicillin)
Research article
  

Microwave Assisted Alternate Synthesis of a Series of Azomethine Derivatives of a Presently Prescribing Semisynthetic Aminopenicillin (Amoxicillin)


Abhilash Mullasseril

Mullasseril, veliyanad post., ernakulam dist., kerala-682 313


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Received: February 18, 2015,   Accepted: March 27, 2015,   Published:


Abstract:

The field of synthesis of organic compounds always incorporates different possible methods for achieving the target compounds. The methods adopted for synthesis must be routed firmly to the green principles in a maximum possible manner. This paper aims the microwave assisted synthesis of a series of azomethine derivatives of widely prescribing semisynthetic penicillin drug called amoxicillin. The microwave assisted synthesis of organic compounds is considered as one of the safest among green methods of the synthesis. For the synthesis of azomethines a series of aromatic aldehydes with varying substituent groups and the drug amoxicillin trihydrate were irradiated using microwave as the source of energy.


Keywords: Amoxicillin; MWAOS; Computer aided Drug designing; Biological activity; Computational methods; Docking


Citation:

Abhilash Mullasseril (2015). Microwave Assisted Alternate Synthesis of a Series of Azomethine Derivatives of a Presently Prescribing Semisynthetic Aminopenicillin (Amoxicillin). J. of Advancement in Medical and Life Sciences. V2I4. DOI: 10.15297/JALS.V2I4.02


Copyright:

© 2015 Abhilash Mullasseril. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.


      
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      Journal of Advancement in Medical and Life Sciences